Cardiac Abnormalities in Alzheimer Disease

Alzheimer Disease: Treatment of Noncognitive Behavioral Abnormalities

Neuropeptide abnormalities in patients with early Alzheimer disease.

BACKGROUND Deficits in somatostatin-like immunoreactivity (SLI) and corticotropin-releasing factor immunoreactivity (CRF-IR) are well recognized as prominent neurochemical deficits in Alzheimer disease (AD). The question of whether these profound neuropeptidergic deficits found in patients with end-stage disease extend into those with much earlier disease is relatively unanswered. To determine ...

Cardiac abnormalities in ischemic cerebrovascular disease.

RESPONSE BY: MASATO NISHIDE, M.D. To the Editor: The study reported by Nishide et al (Stroke 14,541-545, July-August 1983) is of interest in that atrial fibrillation and/or rheumatic heart disease (generally accepted as being associated with an increased risk of systemic thrombo-embolism) were found significantly more frequently in patients presenting with "ischemic cerebrovascular disease" tha...

P 133: Neuroinflammation in Alzheimer ’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder and the most common form of dementia. Almost 47 million people suffer from dementia worldwide. AD accounts for approximately 60%–80% of all dementia cases. Three major pathologies characterize the disease: senile plaques, neurofibrillary tangles and inflammation. We review the literature on events contributing to the inflammat...

Alzheimer abnormalities of the amygdala with Klüver-Bucy syndrome symptoms: an amygdaloid variant of Alzheimer disease.

BACKGROUND Neurofibrillary tangles and beta-amyloid plaques have been observed in the amygdala in Alzheimer disease. A disproportionate abundance of this abnormality in the amygdala may cause behavioral symptoms similar to Klüver-Bucy syndrome. OBJECTIVES To describe an atypical behavioral presentation of Alzheimer disease and to review the literature on the subject. DESIGN Case study. SE...